המדור כולל פרסומים נבחרים של עבודות מחקר עדכניות פרי עבודתם של נוירולוגים בישראל.
עדכונים לגבי פרסומים חדשים ראויים לציון ניתן לשלוח לדוא"ל: stroke@sheba.health.gov.il
אפילפסיה
• Auriel E, Chistik V, Blatt I, Margolin N, Neufeld M. Efficacy and safety of levetiracetam (keppra) add-on treatment in adult patients with refractory epilepsy in two tertiary centers. Harefuah 2007;146:269-71 [Hebrew]
• Gilad R, Sadeh M, Rapoport A, Dabby R, Boaz M,
Lampl Y. Monotherapy of lamotrigine versus carbamazepine in patients with poststroke seizure. Clin Neuropharmacol 2007;30:189-195
• Kipervasser S, Nagar S, Chistik V, Kramer U, Fried I,
Neufeld MY. The prognostic significance of interictal epileptiform activity in postoperative EEGs of patients with mesial temporal lobe epilepsy. Clin EEG Neurosci 2007;38:137-142
• Kipervasser S, Neufeld MY. Video-EEG monitoring of paroxysmal events in the elderly. Acta Neurol Scand 2007;116:221-225
לניטור וידאו EEG תפקיד אבחנתי חשוב בניטור אירועים התקפיים בגיל המבוגר, אולם קיים תת-שימוש בבדיקה זו בגיל המבוגר
הפרעות תנועה
• Djaldetti R, Yust-Katz S, Kolianov V, Melamed E, Dabby R.
The effect of duloxetine on primary pain symptoms in Parkinson disease. Clin Neuropharmacol 2007;30:201-205
דולוקסטין (סימבלטה) נמצא כטיפול יעיל לכאב מרכזי במחלת פרקינסון
• Giladi N, Boroojerdi B, Korczyn AD, Burn DJ, Clarke CE, Schapira AH, SP513 investigators. Rotigotine transdermal patch in early Parkinson\s disease: a randomized, double-blind, controlled study versus placebo and ropinirole. Mov Disord 2007 [Epub ahead of print]
• Hausdorff JM, Lowenthal J, Herman T, Gruendlinger L, Peretz C, Giladi N. Rhythmic auditory stimulation modulates gait variability in Parkinson\s disease. Eur J Neurosci 2007;26:2369-2375
• Hellmann MA, Sabach T, Melamed E, Djaldetti R. Effect of subcutaneous apomorphine on tremor in idiopathic Parkinson\s disease. Biomed Pharmacother 2007 [Epub ahead of print]
• Herman T, Giladi N, Gruendlinger L, Hausdorff JM. Six weeks of intensive treadmill training improves gait and quality of life in patients with Parkinson\s disease: a pilot study. Arch Phys Med Rehabil 2007;88:1154-1158
• Moore O, Peretz C, Giladi N. Freezing of gait affects quality of life of peoples with Parkinson\s disease beyond its relationships with mobility and gait. Mov Disord 2007 [Epub ahead of print]
• Orr-Urtreger A, Shifrin C, Rozovski U, Rosner S, Bercovich D, Gurevich T, Yagev-More H, Bar-Shira A, Giladi N. The LRRK2 G2019S mutation in Ashkenazi Jews with Parkinson disease: is there a gender effect? Neurology 2007;69:1595-1602
• Schlesinger I, Erikh I, Yarnitsky D. Paradoxical kinesia at war. Mov Disord 2007 [Epub ahead of print]
כאבי ראש ופנים
• Granot M, Weissman-Fogel I, Crispel Y, Pud D, Granovsky Y, Sprecher E, Yarnitsky D. Determinants of endogenous analgesia magnitude in a diffuse noxious inhibitory control (DNIC) paradigm: do conditioning stimulus painfulness, gender and personality variables matter? Pain 2007 [Epub ahead of print]
מחלות כלי דם של המוח
• Gur AY, Kesler A, Shopin L, Bornstein NM. Transcranial Doppler for evaluation of idiopathic intracranial hypertension. Acta Neurol Scand 2007;116:239-242
• Lampl Y, Boaz M, Gilad R, Lorberboym M, Dabby R, Rapoport A, Anca-Hershkowitz M, Sadeh M. Minocycline treatment in acute stroke: an open-label, evaluator-blinded study. Neurology 2007;69:1404-1410
לחולים הלוקים בשבץ מוח איסכמי חד שטופלו במינוציקלין היו תוצאים טובים יותר מאשר לאלה שטופלו באינבו
• Telman G, Kouperberg E, Sprecher E, Gruberg L, Beyar R, Yarnitsky D. TCD evaluation before and after stenting in patients with severe primary carotid artery stenosis versus restenosis. J Endovasc Ther 2007;14:483-488
מחלות עצב ושריר
• Drory VE, Artmonov I. Earlier onset and shorter survival of amyotrophic lateral sclerosis in Jewish patients of North African origin. A clue to modifying genetic factors? J Neurol Sci 2007;258:39-43
מחלת ALS מתבטאת בקרב חולים ממוצא צפון אפריקאי בגיל צעיר יותר ובחומרה רבה יותר מאשר בחולים מקבוצות אתניות אחרות
• Kushnir M, Klein C, Kimiagar Y, Pollak L, Rabey JM. Distal lesion of the lateral femoral cutaneous nerve. Muscle Nerve 2007 [Epub ahead of print]
• Leshinsky-Silver E, Argov Z, Rozenboim L, Cohen S, Tzofi Z, Cohen Y, Wirguin Y, Dabby R, Lev D, Sadeh M. Dysferlinopathy in the Jews of the Caucasus: a frequent mutation in the dysferlin gene. Neuromuscul Disord 2007 Sep 5;[Epub ahead of print]
• Leshinsky-Silver E, Michelson M, Cohen S, Ginsberg M,
Sadeh M, Barash V, Lerman-Sagie T, Lev D. A defect in the thymidine kinase 2 gene causing isolated mitochondrial myopathy without mtDNA depletion. Eur J Paediatr Neurol 2007 [Epub ahead of print]
נוירואימונולוגיה
• Achiron A, Doniger GM, Harel Y, Appleboim-Gavish N, Lavie M,
Simon ES. Prolonged response times characterize cognitive performance in multiple sclerosis. Eur J Neurol 2007;14:1102-1108
• Achiron A, Feldman A, Mandel M, Gurevich M. Impaired expression of peripheral blood apoptotic-related gene transcripts in acute multiple sclerosis relapse. Ann N Y Acad Sci 2007;1107:155-167
• Ball-Rosen C, Primak-Rubinovicz H, Korczyn AD, Wang N, Farchi A, Shavit S, Shoenfeld Y, Chapman J. Identification of histidine-rich glycoprotein, a potential autoantigen, in human and rat brain preparations. Ann N Y Acad Sci 2007;1109:473-483
• Friedman-Levi Y, Ovadia H, Hoftberger R, Einstein O, Abramsky O, Budka H, Gabizon R. Fatal neurological disease in scrapie-infected mice induced for experimental autoimmune encephalomyelitis. J Virol 2007;81:9942-9949
• Garin T, Rubinstein A, Grigoriadis N, Nedvetzki S,
Abramsky O, Mizrachi-Koll R, Hand C, Naor D, Karussis D. CD44 variant DNA vaccination with virtual lymph node ameliorates experimental autoimmune encephalomyelitis through the induction of apoptosis. J Neurol Sci 2007;258:17-26
• Grossman I, Avidan N, Singer C, Goldstaub D, Hayardeny L, Eyal E, Ben-Asher E, Paperna T, Pe\er I, Lancet D,
Beckmann JS, Miller A. Pharmacogenetics of glatiramer acetate therapy for multiple sclerosis reveals drug-response markers. Pharmacogenet Genomics 2007;17:657-666
נוירואונקולוגיה ונוירוגנטיקה
• Lavon I, Fuchs D, Zrihan D, Efroni G, Zelikovitch B,
Fellig Y, Siegal T. Novel mechanism whereby nuclear factor kappaB mediates DNA damage repair through regulation of O(6)-methylguanine-DNA-methyltransferase. Cancer Res 2007;67:8952-8959
נוירולוגיה קוגניטיבית
• Buchman AS, Wilson RS, Boyle PA, Bienias JL, Bennett DA. Grip strength and the risk of incident Alzheimer\s disease. Neuroepidemiology 2007;29:66-73
• Shamay-Tsoory SG, Aharon-Peretz J. Dissociable prefrontal networks for cognitive and affective theory of mind: a lesion study. Neuropsychologia. 2007;45:3054-3067
אחר
• Korman M, Doyon J, Doljansky J, Carrier J, Dagan Y, Karni A. Daytime sleep condenses the time course of motor memory consolidation. Nat Neurosci 2007;10:1206-12013